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Comment Re:Like it or not... (Score 1) 81

Like it or not, this ( and others before it ) herald the beginning of the future of transportation.
It will dramatically improve our cities and our lives, and save many lives.

Can't wait for driver-less car settings like in the Amazon series Upload ... :-)
(a) Prioritize occupant.
(b) Prioritize pedestrian.

Comment Re:Off Insulin onto immunosuppressants for life... (Score 2) 64

The immune system problem can be fixed by using each patient's own stem cells.

Type 1 Diabetes is thought to be caused by an autoimmune reaction that destroys the cells in the pancreas that make insulin, so immune-suppressants would be needed anyway. From Type 1 Diabetes:

Type 1 diabetes is thought to be caused by an autoimmune reaction (the body attacks itself by mistake). This reaction destroys the cells in the pancreas that make insulin, called beta cells. This process can go on for months or years before any symptoms appear.

Some people have certain genes (traits passed on from parent to child) that increase their chance of developing type 1 diabetes. However, many of them won't go on to have type 1 diabetes even if they have the genes. A trigger in the environment, such as a virus, may also play a part in developing type 1 diabetes. Diet and lifestyle habits don't cause type 1 diabetes.

The main problem here seems to be that people can have the genetic defect and not have any symptoms until that defect is triggered, like with psoriasis (which I have). I imagine it would be possible to detect this early, if they even know which gene defect it is, and start giving people immune-suppressants to prevent the autoimmune reaction from killing off their own islet cells in the first place, but then even people who would *not* have had developed T1D would be taking the drugs. Perhaps once the defect is nailed down and the analysis is super specific...

Comment Re:Off Insulin onto immunosuppressants for life... (Score 1) 64

Swapping one drug for another, and the second one can lead to direct cancer. Seems smart.

Although... people do this all the time. All those biologic medicines advertised on TV to treat autoimmune conditions like Crohn's disease, rheumatoid arthritis, psoriatic arthritis, psoriasis, and some types of cancer etc... work by suppressing parts of the immune system. The list possible side-effects almost always include, "... tuberculosis and death." Okay, those are super rare, but, for me anyway, my psoriasis isn't bad enough to risk those.

Biologic Medications (Drugs) and Side Effects

Comment Re:Why not use the patients own cells? (Score 1) 64

Seems like that would solve the immunity problem.

It's not (necessarily) about the foreign cells, but the genetic autoimmune condition, triggered by something, that caused their Type 1 Diabetes in the first place.

From this CDC page on Type 1 Diabetes

Causes

Type 1 diabetes is thought to be caused by an autoimmune reaction (the body attacks itself by mistake). This reaction destroys the cells in the pancreas that make insulin, called beta cells. This process can go on for months or years before any symptoms appear.

Some people have certain genes (traits passed on from parent to child) that increase their chance of developing type 1 diabetes. However, many of them won't go on to have type 1 diabetes even if they have the genes. A trigger in the environment, such as a virus, may also play a part in developing type 1 diabetes. Diet and lifestyle habits don't cause type 1 diabetes.

Not a doctor, but I'm guessing it's like Psoriasis (which I have), which is an autoimmune issue enabled by a genetic defect; people can have the defect, but no symptoms until triggered by something, like an injury. This is why drugs and treatments that suppress the immune system work on psoriasis. The difference here is that the autoimmune reaction in T1 Diabetes continually destroys the pancreatic islet cells where the autoimmune reaction in Psoriasis causes too many skin cells to be produced and more quickly than normal. Psoriatic Arthritis (which I don't have, yet anyway) is thought to be also caused by a genetic autoimmune reaction similar to, but slightly different than, that of Psoriasis.

Comment Re:BlueSky is for radicals (Score -1, Flamebait) 70

They could have a) attempted to contact him b) check his twitter where he posted about his plans to create Bluesky account. ZERO effort was spent to verify prior to ban, because this ban was about what he posted (questioning trans orthodoxy). The only reason they unbanned is because this went viral and resulted in tons of bad publicity, any regular user would still be banned.

Comment BlueSky is for radicals (Score -1, Flamebait) 70

"To that end, I found Justice [Clarence] Thomas's concurrence on medical care for transgender youth quite illuminating," Vance wrote, including a screenshot of the conservative justice's statement agreeing with the 6-3 ruling.

Posting this got JD banned from Bluesky. After something like that, you can't pretend that it wants any conservative or moderate posters.

Comment Re:Japan/European (Score 0) 64

Thank God we greatly reduced our funding of science, so now the Japanese and Europeans can make all the science and engineering breakthroughs while we focus on getting more farming and shoe factory jobs.

Duh. Scientists, at the moment, don't pick food or make clothes for rich people, poor(er), usually less-educated, people do.

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