There was a good chance of 23andme being able to make full-genome sequencing (which they weren't yet scaled up to) a commoditized service with the privacy protections that need to be ensured for all customers. However the business model collapsed along the way.

Now we see the most predictable outcome - someone who knows they can profit from the data is buying the remains of the company (with the data).

Only in the USA is the genomic data that valuable, and there is one sector of the economy who can benefit from it more than any other. Regeneron knows which industry that is, and while they aren't a direct part of it themselves they know they need to serve it.

Regeneron bought the data to eventually sell it to the Health Insurance Cartel. The Cartel was granted effective license to print money with the passage of the ACA, but they want more power. They still own an overwhelming majority of congress - on both sides of the aisle - but they want more power. With the genomic data they can start rewriting the rules on pre-existing conditions. As all other plans go up in price they can start offering plans that are less expensive if you consent to DNA testing, which will lead to treatment for some conditions being denied.

We can't win as long as the system is set up this way. We can't change it when the people who benefit from it control the people who set the rules.

The Trump administration has been largely a copy-paste production. When they initially wanted to "replace" the ACA back during his first term, their plan was to replace the ACA with the ACA - made better by putting his signature at the end instead of the signature of President Obama. When they were finally called out on that, they quietly dropped their efforts to repeal the ACA, instead focusing on various things they can do in the name of "border security" (nevermind that no effort has been made this term for the wall that he used to talk nonstop about).

I think you just described humans. WE are the danger to this world, and provide no value to it :)

No one eats viruses but quite a lot of species depend on mosquitoes to survive, or eat the mosquito-eaters to survive.
You don't have to kill any mosquitoes, just replace them with a genetically modified version that is resistant to parasites?

Quite a lot of animals feed on insects, and then some carnivores might feed on them.
If you overfish sardines, anything bigger than a sardine may also suffer a population decline, as it is a staple food for lots of yummy fish and also marine mammals..

Now we just need to determine the world's saddest song to play on it...

Given ByteDance's apparent ties to the Chinese government to ban Tik Tok, this would likely give validation to other countries to ban Facebook, on the same basis. Maybe Meta is looking to get banned elsewhere?

This store reflects a retail model that is simply dead now. You don't go in to a surplus store looking for something specific, as you likely won't find it. You go in with general ideas and you see what you find along the way.

Unfortunately very nearly nobody shops like that any more. We have a chain of surplus stores where I live, and the last several times I've gone in I've walked back out empty handed as they didn't have anything I wanted. They had plenty of things that other people want, but nothing I was looking for at the moment. 500 feet of rope in 12 different diameters? Yep they have it but I'm not looking for it. Cartoon character umbrellas? Yep they have it but I'm not looking for it. Firewire cables? Yep them have them but I'm not looking for them. Strange animated movies I've never heard of? Yep lots of those too. The list goes on and on but if they don't have anything I'm looking for then they won't get any money from me.

Here it’s is more than backup or redundancy. It’s also about limiting the ability of one bad actor to wipe out both the redundant copies and the backups. This likely means a push location, with versioning, that requires someone else’s keys to delete repositories.

The list of 6 speed manual cars sold in the USA is very, very short. If you drop the ones sold by Porsche you cut that list in half. If you then drop the ones from VW (yes I know Porsche is a part of the VW corporate empire but we'll acknowledge them separately here) after that you end up with about 3 vehicles, and you find that even those only offer manual transmissions in very specific configurations.

The bigger news is that this isn't really news, as the manual transmission has been dying a gradual death for decades here. People don't learn it, and they don't want to drive it. On the plus side it makes it a theft deterrent technology for those who do drive it.

I grew up down the street from her house. Went to the first Chuck E Cheese's across the street often.

Civilization didn't collapse due to her house. It wasn't even the first revision of her house (IIRC got leveled in the great SF earthquake) There's a lot of people that look at the Victorian adornments of her house as a sign we had civilization. Compared to the Soviet Bloc style housing we have going in today that has surrounded it, the Winchester house now looks out of place.

All kind of sad really. Town and Country was a beautiful shopping center. The trailer park next door provided low income housing, and the Styufy dome theatres looked straight out of a moonbase. Nothing is allowed to have exposed wood beams or rounded edges anymore.

In reality the companies lost only the cost of the DVDs.

And consumers aren't willing to pay more money, unless its something niche. The problem maintaining a small outfit. unless there are ways to reduce maintenance fees?

So the tariffs are only impacting China and not doing anything to bring jobs back to the US? Not sure whether thatâ(TM)s considered winning?

Very insightful. Very few things are truly a zero-sum game in life,
that attitude completely discounts any win-win situations stupidly, selfishly and needlessly.

Yet, the firings and beatings will continue until morale improves!