With those self-driving SUVs but you've got the semi trucks and those things can easily kill and they can kill a lot.
My friend's cousin got rear-ended by a semi truck that didn't see the red light at the end of the off-ramp, or the car that was stopped at it. He was instantly killed, his car was crushed like a can.
It turned out the semi's driver had been on the road for 14 hours straight, and was not, shall we say, in a fully lucid state.
Would a self-driving truck have avoided this death? It's hard to say for sure, but we can probably at least say that its cognitive abilities wouldn't degrade over the course of a long day, due to lack of sleep.