Comment Re:It's not Lupus (Score 1) 28
That's not the goal of a vaccine against a dormant virus (destroying B-cells), it's about developing a more capable immune reaction against the virus itself. See for example the shingles vaccine (targets dormant VZV, aka shingles / chickenpox). With a strong immune recognition of the virus, as soon as it tries to reactivate, it's immediately targeted, preventing it from becoming problematic.
Dormant viruses use a combination of (A) techniques to suppress immune recognition of them, and (B) low / no reproduction until your body's immune recognition of them has weakened. Vaccines help deal with both issues.
(BTW, if you're getting up there in age and haven't gotten your shingles vaccine, do so. It's one of the "rougher" vaccines, IMHO (both on my initial and followup doses I had "flu symptoms" for a day, when I normally have no reaction at all to vaccines), but that's *way* better than getting shingles)