I bought my spouse a Dymo 400 for xmas ($80 or so at amazon). I was amazed by its speed and ease. One caveat: it came with a label test halfway stuck in and out of the case, without instructions for removing it. Needless to say, I chose to pull it the wrong way, and ended up with bits of label sticker stuck inside the thing. Didn't make for a happy xmas morning. Once I got it out it works great. I tested it on OS X and XP. No printer cartridges either. Deal.