Placebo trials are the gold standard for conditions that do not have an existing treatment.

The gold standard for evaluating new treatments is a double blind study with both the old and new treatment.

When there is an existing treatment, a placebo based double blind study is simply impossible. There is no way to get it past the ethics review board, because the study would leave half the participants completely unprotected.

Even if for some reason a placebo trial was approved, guess what? If it successful, the next step is, you guessed it, test the new treatment against the old treatment to see if it is even worthwhile, i.e., a double blind study with both the old and new treatments.

A placebo trial tell you if the treatment is better than nothing, but the only question worth asking is, is it better than what we have now?

In short, the entire "Must be a placebo trial" is just a thinly veiled anti-vaxxer effort to make new vaccines impossible to approve in the USA. Not only do the anti-vaxxers want to skip the vaccines, they want to make it impossible for anyone else to get them either.

A placebo trial tell you if the treatment is better than nothing, but the only question worth asking is, is it better than what we have now?

So, if you are wondering "if not this much, then how much?" (which is a very good question), how about we look at the charges for the Canadian Federal system?

Obviously the US can't just say "Do that!", but it should give some ballpark estimates of what is reasonable. Values here are "prisoner paid", not collect.

Local $0.475 per call/message
National $0.045 per minute
United States $0.05 per minute
International $0.06 per minute

Local rates are 48 cents **per call**. Call length usually limited to one hour.

https://ancillary-proxy.atarimworker.io?url=https%3A%2F%2Fwww.canada.ca%2Fen%2Fcorre...

The idea is that all the rights that currently go with marriage would transfer to civil unions. The Gov't recognizes civil unions.

If people ALSO want to have a marriage ceremony to go with their civil union, go right ahead. The civil union part is the legal part though.

Basically, completely remove the religious aspect of marriages, and what do you have? Call that the civil union. People can then add their own religious practices on top of that.

One great thing about it is that it helps further separate religion and Gov't, an always laudable goal.

Unlike the USA, Canada isn't going to be stupid about tariffs. For example, maybe a tariff on USA wine and liquor. Absolutely minimal harm to Canadian consumers, because we can get stuff just as good from other places.

We already get fruit and veg from around the world, dropping some stuff grown in the USA isn't going to make much difference.

Just because the USA decided to use blanket tariffs doesn't mean everyone else has to play the same incredibly stupid game. Unlike the USA, we will likely listen to experts, and target things that will hurt USA exporters, and harm Canadians in only minimal ways.

Of course, there are other options as well. Oh, so now our aluminum is a problem. Fine, we'll just sell it to someone else. I'm sure the auto and aerospace sectors can scare up new suppliers, right?

So take advantage of that. A valve held open with a fusible link, with a spring to drive it shut when the link breaks.

They already exist, they're used in the petro-chem industry.

Nope, fusion creates heat. The photons you see from the sun all are created by thermal emission at the surface.

Why would you wait to have your receipt checked? There's no membership (like at Costco) to impose more rules on you.

Just walk out. If they ask you to wait, say "No thanks!".

It is 1000% *of* the original price.
It is a 900% *increase* over the original price.

"Trump Derangement Syndrome". It's a phrase used by Trump supporters to wave away all criticism of Trump.

In the Trump supporters' minds, since Trump is a Good Guy (TM), all criticism of him must be based on self delusion, so all people critical of Trump must be deranged.

Like most derogatory statements from the modern American conservative movement, it says much more about themselves than it does about the people they are targeting.

"Computers are useless.They can only give you answers"

  - Pablo Picasso

You don't. If it needs servicing, you haul it to the surface, open the doors and air it out, then do your servicing.

Close it up, purge it and drop it overboard.

I imagine the idea was that you basically don't service it - just leave the failing hardware there until it makes sense to do a major overhaul.

You say that like it's a bad thing. If the only way to be profitable is to operate to the detriment of everyone else, then why should the rest of us allow it?

You might care if the car you're in gets into an accident, you need thousands of dollars of healthcare, and THEN you find out that the driver's insurance has been voided because 'reasons'.

Part of licensing is the attendant regulation, things like valid insurance.

While sometimes true, I doubt that all teachers are so ignorant. I think the problem is simply that the curriculum is centered around what is easy to test, rather than what is useful to know.

Teachers don't set the curriculum, the blame lies elsewhere.

So the teacher takes the phone, sticks it in a drawer, and tells the student they can get it back when they come back for detention.

Don't let 'Perfect' be the enemy of 'Good Enough'.