I think that method of administration has a lot to do with it as well, since consuming involves the digestive system and it's tendency to degrade proteins... a major barrier to administering many drugs

Beyond that, once it makes its way to the blood stream, any drug still needs to cross the blood-brain barrier.

Due to the vagaries of reporting, the mice may have been given a 5mg object, with some amount of psilocybin in it to eat, or they may have had a tube to the spinal column administering straight to the brain

I agree that initiating a medical study with a lethal dose of the agent does not make sense

I'll concede that my main point ignored microdosing, which may be considered common, there are reasons us old guys shout at the sky

Harder to accomplish than you would expect, far easier to join The Peyote Way Church of God, and set up your own spirit walk

You do realize that attempting to control people though fear is sooooo last millennia

Of course you don't want children using any mind altering substances, unless it's ritilin, adderall, sri's etc...

Funny thing, I grew up in the 70's, and as feral children, we were drawn to the forbidden. By the time I was 18 I had direct experience with a number of hallucinogens, and... not dead

What HAS been a direct issue for people I have known are pharmaceuticals, or their street analogs, opioids, amphetamines and even good ole' "natural" cocaine

The unfortunate addition of all hallucinogens to DEA schedule 1 list, tied to the APA's insistence that they cause mental illness, along with the international conventions on drug control, has prevented real medical study and prevented doctors, therapists, even inDUHviduals access to something with real benefits

So I get it, we are supposed to give up so many good things, "FOR THE CHILDREN", because... why?

*sigh*

go play in reddit , child and get offa my lawn

Australians seem friendly enough, but I have watched Mr Inbetween, so I am more wary now

Arizonan here, our spiders will cause deep lesions, rattlesnakes will kill or maim you, one of the hastiest ants is widespread, BUT you can lick our toads and have a religious experience

It is far too dry in most of the state for wild psilocybin to be available, but the local shamans have a wide range of psychoactives they have used for centuries

Come for the weather (118F yesterday), stay for the mind alterations

The COST of a dose of mushroom is TINY compared to the RISK of criminal prosecution and the associated costs that go with arrest and prosecution

Not sure where you are coming from, but for me a longer life means a longer working life, mainly because I ENJOY my work

For the common species Psilocybe cubensis, a gram of dried mushrooms can contain 10–12 mg of psilocybin

I am pretty sure that most humans are taking 3-7 grams of mushrooms when they dose

Just sayin

The original plans for Palo Verde were 6 reactors, AFAIK they still own the land and other rights associated with the expanded capacity

One of the problems with the commoditization of Slashdot has been the selling of dormant low-uid accounts to these propagandists

The Nazi apparatus leveraged the existing German press, who promoted the idea that Germany was going to win WW1 until they were sold out by the Jewish bankers

It was this propagandizing through the press that destroyed critical thinking in Germany and allowed Hitler to take over with a constant stream of lies and constant blaming others for Germany's failures

This is EXTREMELY similar to the effect that Fox News has had on the American right wing and turned them into propagandized idiots who are open to all of Trumps lies and assertion of blame on others

Ends justifies the means?

What could possibly go wrong...

You say you want "free speech", but with X you are advocating for propaganda and lies that are being used to drive the populace into idiocy

And you are the one killing off monarch butterflies and bees with your obsession vision of a perfect lawn

Pollinators that are attracted to your pesticide laden 'flowers', (probably not local species they are adapted to), take it back to their hive and hurt the entire colony, while monarch butterflies rely on milkweed, something that only appears in untended lawns, and exceeds the weed height allowed by most municipalities