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Comment Why is the EFF tied to fiber? (Score 1) 204

The specification of fiber-everywhere should be replaced with a goal of broadband-everywhere (defined as > X Gbps, where X is defined by some balance of cost-performance based on current technologies and X increases over time.)

A lot of us on /. are technical and in engineering-like professions and hobbies. So, why would we demand a specific technology instead of looking at how we can deliver faster broadband to more places in the most economically-efficient way.

Without a doubt, the most economically efficient way to provide broadband to rural areas is via wireless, whether it is via terrestrial antennas/repeaters (LTE, 5G, VHF/UHF/ microwave) or satellite (currently geosynchronous high-latency, but soon with much lower-latency via a LEO constellation).

The US governmental agencies can be involved by lowering the regulatory hurdles for building more cell/radio towers, opening up more RF spectrum, and allowing LEO satellite constellations to be built-out. To do so, would even add competitive pressure to the areas where cable and telephone companies have local monopolies and force them to improve their service to their users, too.

Comment Initially failed, but then worked after safe mode (Score 1) 90

I had an installation problem when installing the macOS 10.13.4 update on my MacBook Air.

After rebooting, my system would crash (requiring a reboot) ad nauseam.

I rebooted in Safe Mode and somehow got the machine out of the annoying reboot cycle. At that point, I rebooted back int 10.13.3 and resolved not to upgrade to 10.13.4 until I heard it was safe to install. When I went to the App Store and checked for updates, the 10.13.4 update disappeared from the list. (It seemed at the time that Apple had pulled it from their servers.) Unfortunately, a week or so later, the update was pushed down and my machine rebooted. But, it seemed to work this time, fortunately.

Reviewing the logs, there was an entry about a file not found which seemed to cause the problem. I didn't save the logs, so I can't report the exact error.

Comment Re:The Next Generation of Immunotherapy Works (Score 3, Interesting) 73

That's a good question, and I'm not certain that the researchers could definitively say yes or no.

I should note that the white blood cells (lymphocytes) that were grown in the lab were those selected to attack the cancerous cells. Some of those T lymphocytes may also have the "memory" for identifying the other foreign items from which I've already acquired immunity. In addition, as part of the treatment, twenty-four hours after receiving the new white blood cells that were grown in the lab, I was given a pint of the blood stem cells that were extracted before treatment, mostly to counteract the effects of the total body radiation on the stem cells in my bone marrow for the trial. (The researchers were trying to determine if they got better survival results with this treatment by giving 12 Grays of radiation versus no radiation. Ultimately, they determined from the trial that the radiation showed little improvement in overall survival.)

I do know that my allergies have changed since my treatment. In fact, they've moderated a bit. My first month or so after treatment, it seemed like I had seasonal allergies to everything, but that has pretty much faded away and ragweed and cottonwood seasons don't seem to affect me much anymore.

Also, my doctors had me on an antibiotic (Bactrim) for at least six months post-treatment, because of the increased risk of contracting a certain type of pneumonia (PCP) because of my suppressed immune system.

Comment The Next Generation of Immunotherapy Works (Score 5, Informative) 73

I'm living proof these sorts of immunotherapy treatments work: five years and still cancer-free. It's wonderful that the FDA may be on the brink of approving their use outside of trials.

I sought out and was admitted into a trial at NIH in 2012 to use a similar treatment for Stage IV melanoma.

In my trial, the researchers harvested my existing white blood cells and selected those that were able to recognize and attack the mutations present in my melanoma. Those cells were expanded to 130 billion in the lab and then re-infused into my body after my own immune system was killed off. In essence, my immune system was rebooted with white blood cells that could recognize and fight the cancer cells.

In theory, my body has been effectively immunized against the some of the cancerous mutations that my melanoma exhibited. I won't need any further treatment for my previous melanoma EVER.

I know fellow melanoma patients who were in related trials at NIH in which their harvested white cells were genetically engineered to express different proteins (like, IL-12 or IL-15 or NY/ESO) with similar success.

These novel cancer-fighting approaches are working. I'm happy that the FDA may actually be slowing adapting to the changing medical technology.

Comment Re:Skyhook's implementation really is inventive (Score 1) 78

I had the same problem with SkyHook this last month. I set up my Airport Extreme in my hotel room in San Francisco for WWDC. When I re-used it on a visit to Northern Wisconsin (where there was no cell phone, much less AT&T service), my iPhone always reported its location as the hotel I was staying at in San Francisco. Frankly, I was surprised that SkyHook picked up my new access point in the short amount of time that I had it up and running in San Francisco.

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