The complexity of biochemical pathways has to do with differential concentrations of substrates and products. These enzyme logic systems sound like they have the potential to "light up" cascades of cellular "output". Very cool tools, from a research perspective.

Perhaps this technology could be used to examine some of these pathways in more detail: Cellular metabolism - gluconeogenesis, citric acid cycle, stuff going on in mitochondria and chloroplasts, diabetes, etc.

Cancer - Pathways of loss/gain of function mutations which result in tumor formation

Make no mistake - systems like these have the potential to "hack the cell" in a much more standardized fashion.