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Submission + - What are the most highly cited scientific papers of all time? (nature.com)

bmahersciwriter writes: Citation is the common way that scientists nod to the important and foundational work that preceded their own and the number of times a particular paper is cited is often used as a rough measure of its impact. So what are the most highly cited papers in the past century plus of scientific research? Is it the determination of DNA's structure? The identification of rapid expansion in the Universe? No. The top 100 most cited papers are actually a motley crew of methods, data resources and software tools that usability, practicality and a little bit of luck have propelled to the top of an enormous corpus of scientific literature.

Submission + - Detritus from cancer cells may infect healthy cells (nature.com)

bmahersciwriter writes: Tiny bubbles of cell membrane — called exosomes — are shed by most cells. Long thought to be mere trash, researchers had recently noticed that they often contain short, regulatory RNA molecules, suggesting that exosomes may be one way that cells communicate with one another. Now, it appears that RNA in the exosomes shed by tumor cells can get into healthy cells and 'transform' them, putting them on the path to becoming cancerous themselves.

Submission + - How to read a microbiome study like a scientist.

bmahersciwriter writes: Scientific reports have increasingly linked the bacteria in your gut to health and maladies, often making wild-sounding claims. Did you hear about the mice who were given fecal transplants from skinny humans and totally got skinny! Well, some of the more gut-busting results might not be as solid as they seem. Epidemiologist Bill Hanage offers five critical questions to ask when confronted by the latest microbiome research.

Submission + - Mapping a monster volcano (nature.com)

bmahersciwriter writes: In one of the biggest-ever seismology deployments at an active volcano, researchers are peppering Mount St Helens in Washington state with equipment to study the intricate system of chambers and pipes that fed the most devastating eruption in US history. This month, they plan to set off 24 explosions — each equivalent to a magnitude-2 earthquake — around around the slumbering beast in an effort to map the its interior with unprecedented depth and clarity.

Submission + - How did those STAP stem cell papers get accepted in the first place? (nature.com)

bmahersciwriter writes: The news team at the scientific journal Nature turns its investigative power on the journal itself. The goal: to try and understand how two papers that made extraordinary claims about a new way to create stem cells managed to get published despite some obvious errors and a paucity of solid evidence. The saga behind these so-called STAP cells is engaging, but sadly reminiscent of so many other scientific controversies. Why is science so bad at policing itself?

Submission + - Getting the most out of the space station (before it's too late)! (nature.com)

bmahersciwriter writes: NASA administrators are strategizing a push to do more science on the International Space Station in the coming years. The pressure is on, given the rapidly cooling relations between the US and Russia whose deputy prime minister recently suggested that US astronauts use a trampoline if they want to get into orbit.
Aiding in the push for more research is the development of two-way cargo ships by SpaceX, which should allow for return of research materials (formerly a hurdle to doing useful experiments). NASA soon aims to send new earth-monitoring equipment to the station and expanded rodent facilities. And geneLAB will send a range of model organisms like fruit flies and nematodes into space for months at a time.

Submission + - A disease that's blowing in the wind (nature.com)

bmahersciwriter writes: Kawasaki disease is a mysterious condition that results in alarming rashes, inflammation and sometimes early death. It has affected communities in Japan at unpredictable intervals for decades, and is suspected to arrive there and elsewhere by the wind (http://www.nature.com/news/infectious-disease-blowing-in-the-wind-1.10374). Now, researchers have narrowed the source to croplands in northern China and offered some possible explanations as to its cause.

Submission + - Curiosity Rover may have brought dozens of microbes to Mars (nature.com)

bmahersciwriter writes: Despite rigorous pre-flight cleaning, swabbing of the Curiosity Rover just prior to liftoff revealed some 377 strains of bacteria.
"In the lab, scientists exposed the microbes to desiccation, UV exposure, cold and pH extremes. Nearly 11% of the 377 strains survived more than one of these severe conditions. Thirty-one per cent of the resistant bacteria did not form tough, protective spore coats; the researchers suspect that they used other biochemical means of protection, such as metabolic changes."
While the risk of contaminating the red planet are unknown, knowing the types of strains that may have survived pre-flight cleaning may help rule out biological 'discoveries' if and when NASA carries out it's plans to return a soil sample from Mars.

Submission + - Zombie plants help to spread bacterial pathogen (nature.com)

bmahersciwriter writes: We've all heard stories about how parasites can 'zombify' organisms, getting them to mindlessly protect a brood or infect their peers. Now UK researchers have figured out how one bacterial pathogen co-opts the behaviour of a plant, causing it to attract sap-sucking insects that help the bacteria spread to other plants.

From the story in Nature News:

“The plant appears alive, but it’s only there for the good of the pathogen,” says plant pathologist Saskia Hogenhout from the John Innes Centre in Norwich, UK. “In an evolutionary sense, the plant is dead and will not produce offspring.”

“Many might baulk at the concept of a zombie plant because the idea of plants behaving is strange,” says David Hughes, a parasitologist at Pennsylvania State University in University Park. “But they do, and since they do, why wouldn't parasites have evolved to take over their behaviour, as they do for ants and crickets?”

Submission + - More troubles for authors of controversial acid-bath stem cell articles. (nature.com)

bmahersciwriter writes: Reports early this year about a strikingly simple method for deriving pluripotent stem cells were met with amazement and deep scepticism, then claims that the experiments were not reproducible, then accusations of copied and manipulated figures. Now, the first author of one of the papers is being lambasted for having copied the first 20 pages of her doctoral thesis from an NIH primer on stem cells. And an adviser on her thesis committee says he was never asked to review it. Could this get any stranger? Probably!

Submission + - Dinosaurs done in by ... dark matter? (nature.com)

bmahersciwriter writes: Theoretical physicists propose that the Sun periodically crosses into a dense layer of dark matter sandwiching the Milky Way. The gravitational push and pull that this creates disturbs debris in the Oort cloud sending deadly comets and asteroids ricocheting around the solar system. This passage happens, their admittedly speculative model suggests, every 35 million years, which jibes somewhat with evidence on impact craters. Take it with a dino-sized grain of salt.

Submission + - Scientists thaw a giant 30,000 year old virus, and it's infectious. (nature.com)

bmahersciwriter writes: It might be terrifying if we were amoebae. Instead, it's just fascinating. The virus, found in a hunk of Siberian ice, is huge, but also loosely packaged, which is strange says evolutionary biologist Jean-Michel Claverie: “We thought it was a property of viruses that they pack DNA extremely tightly into the smallest particle possible, but this guy is 150 times less compacted than any bacteriophage [viruses that infect bacteria]. We don’t understand anything anymore!”

Submission + - Publishers withdraw more than 120 fake papers (nature.com)

bmahersciwriter writes: Over the past two years, computer scientist Cyril Labbé of Joseph Fourier University in Grenoble, France, has catalogued computer-generated papers that made it into more than 30 published conference proceedings between 2008 and 2013. Sixteen appeared in publications by Springer, which is headquartered in Heidelberg, Germany, and more than 100 were published by the Institute of Electrical and Electronic Engineers (IEEE), based in New York. Both publishers, which were privately informed by Labbé, say that they are now removing the papers.

Submission + - Whistle blowing in action (nature.com)

bmahersciwriter writes: Helene Hill thought she was close to retirement when, on a whim one day, she decided to check on a junior colleague's cell cultures. They were empty, she says, yet he produced data from them soon after. Blowing the whistle on what she thinks was research misconduct cost her 14 years and $200,000. See how she and other whistleblowers fared in this story from Nature.

Submission + - Croak & Dagger: Following the trail of a herpetologist spy. (nature.com)

bmahersciwriter writes: When Rafe Brown started doing field research in the Philippines, he constantly found himself in the long shadow of, Edward Taylor — an irascible giant of herpetology from the mid 20th century whose legacy was tarnished by accusations of fraud, questions about his naming methods, and rumours of a double life working for the U.S. Government. Brown forged a bond with his predecssor and has begun to restore a collection of Taylor's specimens that were lost during the Second World War, and which could aid in allocating resources for conservation. He has meanwhile found out more about Taylor's extracurricular activities, which included work with the organization that would eventually become the CIA.

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