Hugh Pickens writes "BBC reports that more people need to donate their brains to medical research if cures for diseases like dementia are to be found and are urging healthy people as well as those with brain disorders to become donors. 'For autism, we only have maybe 15 or 20 brains that have been donated that we can do our research on. That is drastically awful,' said Dr Payam Rezaie of the Neuropathology Research Laboratory at the Open University. 'We would need at least 100 cases to get meaningful data. A lot of research is being hindered by this restriction.' Part of the problem, according to Professor Margaret Esiri at the University of Oxford, may be that people are reluctant to donate their brains because they see the organ as the basis of their identity. 'It used to be other parts of the body that we thought were important,' says Esin. 'But now people realize that their brain is the crucial thing that gives them their mind and their self.' Dr Kieran Breen, of the Parkinson's Disease Society, said over 90% of the brains in their bank at Imperial College London were from patients, with the remaining 10% of 'healthy' brains donated by friends or relatives of patients. 'Some people are under the impression that if they sign up for a donor card that will include donating their brain for research. But it won't,' says Breen. 'Donor cards are about donating organs for transplant, not for medical science.'"

gregg writes "Six weeks before the nation's television stations are scheduled to convert to digital transmission, the Obama administration is asking Congress to consider a delay. In the most significant sign to date of concern about the impending digital TV transition, the Obama transition team co-chair John Podesta said the government funds to support the change are 'woefully inadequate' and said that the digital switch date, Feb. 17, should be 'reconsidered and extended.'"

Harry writes "Most folks think that Microsoft Office's Clippy, Microsoft Bob, and Windows XP's Search Assistant dog were perverse jokes — but a dozen years' worth of patent filings shows that Microsoft took the concept of animated software 'helpers' really, really seriously, even long after everyone else realized it was a bad idea. And the drawings those patents contain are weirdly fascinating." The article, a slide show really, spreads over 15 pages.

Lumpy writes "I am giving several new PC's to a local charity that will be giving them to needy kids this Xmas. They are not powerful, basically baseline Dells that have Intel graphics and Celeron, but more than enough to do homework and other studies on. They are going out with XP on them, an Ubuntu CD, and a bunch of OSS software like OO.o and the others. I would like to include some games for the kids. Strategy, fun, etc. Great freeware games that are fun to play. What would be the best games that a 13-16 year old will like to play that are free and legal to give away, and will run on this lower-end hardware?"

Since shortly after its release in late 2004, World of Warcraft has held the position of the most popular MMO, quickly outstripping predecessors such as Everquest and Ultima Online, and continuing to hold the lead despite competition from contemporaries and newer offerings, like Warhammer Online. When World of Warcraft's first expansion, The Burning Crusade, was released, it built on an already rich world by using feedback from players and two extra years of design experience to work on condensing the game to focus more on the best parts. Now, with the release of Wrath of the Lich King, Blizzard seems to have gotten themselves ahead of the curve; in addition to the many changes intended to remove the "grind" aspect that is so prevalent in this genre, they've gone on to effectively put themselves in the player's shoes and ask, "What would make this more fun? Wouldn't it be cool if..?" Read on for the rest of my thoughts.

myrdos2 writes "A host of common chemicals is feminizing males of every class of vertebrate animals, from fish to mammals, including people. Many have been identified as 'endocrine disruptors' or gender-benders because they interfere with hormones. Communities heavily polluted with gender-benders in Canada, Russia, and Italy have given birth to twice as many girls as boys, which may offer a clue to the mysterious shift in sex ratios worldwide. And a study at Rotterdam's Erasmus University showed that boys whose mothers had been exposed to PCBs grew up wanting to play with dolls and tea sets rather than with traditionally male toys. It also follows hard on the heels of new American research which shows that baby boys born to women exposed to widespread chemicals in pregnancy are born with smaller penises and feminized genitals. It is calculated that 250,000 babies who would have been boys have been born as girls instead in the US and Japan alone. And sperm counts are dropping precipitously. Studies in more than 20 countries have shown that they have dropped from 150 million per milliliter of sperm fluid to 60 million over 50 years."

Dave Knott writes "The CBC's weekly science radio show Quirks and Quarks this week features a countdown of the top ten planetary doomsday scenarios. Nine science professors and one science fiction author are asked to give (mostly) realistic hypotheses of the ways in which the planet Earth and its inhabitants can be destroyed. These possibilities for mankind's extinction include super-volcanoes, massive gamma ray bursts, and everybody's favorite, the killer asteroid. Perhaps the most terrifying prediction is the reversal of the Earth's magnetic field (combined with untimely solar activity), a periodic event which is currently 1/4 million years overdue."

WillDraven is just one of many who writes to tell us that Circuit City, the United States' 2nd largest consumer electronics retailer, has filed for bankruptcy under chapter 11. This news comes as no surprise as the company has been in financial trouble, recently announcing that it will be closing over one fifth of its stores and laying off 17% of its US employees in the process. "Larger rival Best Buy, which is based in Minneapolis, has said it might take over stores that distressed rivals close. Yet a flood of discounted merchandise from liquidating Circuit City stores could hurt Best Buy during this holiday shopping season, said Jefferies & Co analyst Dan Binder."

carusoj writes "Squatting on domain names is nothing new, but Twitter has created a new opportunity for squatters, in the form of Twitter IDs. Writes Richard Stiennon: 'Is there evidence of Twitter squatting (squitting?) Let's check. Yup, every single-letter TwitID is taken ... How about common words? Garage, wow, war, warcraft, Crisco, Coke, Pepsi, Nike, and Chevrolet are all taken. My guess is that Twitter squatters have grabbed all of these in the hopes that they will be worth selling in the not too distant future. Of course the legitimate holders of brands can sue for them and Twitter can just turn them over if asked. But, because the investment and risk for the squatter is zero, you are going to see the rapid evaporation of available Twitter IDs.'"

An anonymous reader writes "API Lead at Twitter, Alex Payne, writes today that the Internet was 'built wrong,' and continues to be accepted as an inferior system, due to a software engineering philosophy called Worse Is Better. 'We now know, for example, that IPv4 won't scale to the projected size of the future Internet. We know too that near-universal deployment of technologies with inadequate security and trust models, like SMTP, can mean millions if not billions lost to electronic crime, defensive measures, and reduced productivity,' says Payne, who calls for a 'content-centric approach to networking.' Payne doesn't mention, however, that his own system, Twitter, was built wrong and is consistently down."

An anonymous reader writes "Valleywag says the Jerry Seinfeld ads are over — In a phone call, Frank Shaw confirms that Microsoft is not going on with Seinfeld, and echoes his underlings' spin that the move was planned. There is the 'potential to do other things' with Seinfeld, which Shaw says is still 'possible.' He adds: 'People would have been happier if everyone loved the ads, but this was not unexpected.'"

theodp writes "Instead of laying off techies who directly help users, Robert X. Cringely argues that the best place to cut IT organizations is at the top. One of the great problems in IT management, Cringely says, is that the big bosses typically haven't a clue what is happening, what needs to happen, and what it all should cost. He issues the following challenge: 'If you are managing an IT shop and can't write the code to render "hello world" in C, HTML, PHP, and pull "hello world" from a MySQL database using a perl script, then you are in the wrong job.' Even with help from Google, Cringely believes many technical managers would fail this test and should get the boot as a result — you can't manage what you don't understand."

An anonymous reader writes "From the EFF webpage: 'Over a period of twelve hours, between this Thursday night and Friday morning, American Rights Counsel LLC sent out over 4000 DMCA takedown notices to YouTube, all making copyright infringement claims against videos with content critical of the Church of Scientology.'"

chrb writes "BBC News is reporting that laptops taken to the International Space Station by NASA astronauts are infected with the Gammima.AG worm. The laptops have no net connection; officials suspect the worm may have been transferred via a USB flash drive owned by an astronaut. NASA have said this isn't the first time computer viruses had travelled into space."

dominique_cimafranca notes a story up at the Daily Mail in the UK about a partially paralyzed man who is able to walk again using an exoskeleton frame. The article goes a bit far in comparing the device to Robocop, but it does show pictures of the man, paralyzed for the last 20 years, regaining some use of his legs. Quoting: "The device, called ReWalk, is the brainchild of engineer Amit Goffer, founder of Argo Medical Technologies, a small Israeli high-tech company. Something of a mix between the exoskeleton of a crustacean and the suit worn by Robocop, ReWalk helps paraplegics — people paralyzed below the waist — to stand, walk and climb stairs. The system, which requires crutches to help with balance, consists of motorized leg supports, body sensors and a back pack containing a computerized control box and rechargeable batteries."