He's a neuroendocrinologist that has logged lots of hours on youtube to help us understand sugar/fat metabolism, and how the food industry has been damaging us for decades. The most salient point is that the day of the calorie is past. Bomb calorimeters relate thermal energy to dietary-sourced energy, which is not relevant to dietary awareness. One real culprit is thought to be fructose as its a toxin to our mitochondria. Glucose will just make us fat. Google the good doctor, and be informed. He advises the medical industry to differentiate LDL into 2 primary constituents - Buoyant form, and the Remnant form... former is less the concern... and the latter ( VLDL?) is the one that is the one to watch. Yeah... i am learning, on the road to better health.. Don't eat food with barcodes. Odd that preservatives keep food from spoiling because its not processed by bacteria. that doesn't turn off when we eat it.. our guts are based on bacteria. Do the math. Things we can improve: relevant blood tests, moving past the stating-for-all (that can push us towards diabetes ironically) targeting the bad things in UPF. Please review and support Dr Lustigs effort - he seems the most altruistic of the on-line doctors. Start googling "lustig ultimate guide" - protect the liver, feed the gut, and support the brain.