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Medicine

Why Most Published Research Findings Are False 259

Hugh Pickens writes "Researchers have found that the winner's curse may apply to the publication of scientific papers and that incorrect findings are more likely to end up in print than correct findings. Dr John Ioannidis bases his argument about incorrect research partly on a study of 49 papers on the effectiveness of medical interventions published in leading journals that had been cited by more than 1,000 other scientists, and his finding that, within only a few years, almost a third of the papers had been refuted by other studies. Ioannidis argues that scientific research is so difficult — the sample sizes must be big and the analysis rigorous — that most research may end up being wrong, and the 'hotter' the field, the greater the competition is, and the more likely that published research in top journals could be wrong. Another study earlier this year found that among the studies submitted to the FDA about the effectiveness of antidepressants, almost all of those with positive results were published, whereas very few of those with negative results saw print, although negative results are potentially just as informative as positive (if less exciting)."
Google

Mozilla's Thoughts On Google's Chrome 604

tandiond writes to tell us that in a recent blog posting, Mozilla CEO John Lily shared his thoughts on Google's new browser project, Chrome, and what that means for Mozilla. "It should come as no real surprise that Google has done something here — their business is the web, and they've got clear opinions on how things should be, and smart people thinking about how to make things better. Chrome will be a browser optimized for the things that they see as important, and it'll be interesting to see how it evolves." Mozilla's Europe president, Tristan Nitot also chimed in during an interview with PCPro, stating that they don't view this as a direct attack on Firefox, even if it did catch them by surprise. "I'll take another example: just before Microsoft launched Vista, it invited us [to work with it] so that Firefox works better on Windows Vista. Because for it, Firefox being a top-tier application that was very successful - we now have 200 million users around the world - it could not afford to have Firefox run slowly on Vista. Therefore, it helped us improve Firefox for Vista. That's just the same for Google. It wants Firefox to perform well with its applications, that's for sure. Indeed, it even wants IE to perform well with Gmail and the rest. It's just that it has very limited control over this. That's why Google's been frustrated and it is launching this Chrome browser."
Internet Explorer

IE8 Beta 2 Fatter Than Firefox and XP 597

snydeq writes "Consuming twice as much RAM as Firefox and saturating the CPU with nearly six times as many execution threads, Microsoft's latest beta release of Internet Explorer 8 is in fact more demanding on your PC than Windows XP itself, research firm Devil Mountain Software found in performance tests. According to the firm, which operates a community-based testing network, IE8 Beta 2 consumed 380MB of RAM and spawned 171 concurrent threads during a multi-tab browsing test of popular Web destinations. InfoWorld's Randall Kennedy speculates that Microsoft may be designing IE8 for the multicore future. But until your machine sports four or eight discrete processing cores, IE8 will remain 'porcine,' Devil Mountain's Craig Barth says."
Space

The Sun Has First Spotless Month Since 1913 571

radioweather writes "August 2008 has made solar history. As of 00 UTC September 1st 2008 (5PM PST) we just witnessed the first spotless calendar month since June 1913.This was determined according to sunspot data from NOAA's National Geophysical Data Center, which goes back to 1749. In the 95 years since 1913, we've had quite an active sun, but activity has been declining in the last few years. The sun today is a nearly featureless sphere and has been spotless for 42 days total, but this is the first full calendar month since 1913 for a spotless sun. And there are other indicators of the sun being in a funk. Australia's space weather agency recently revised their solar cycle 24 forecast, pushing the expected date for a ramping up of cycle 24 sunspots into the future by six months." As one of the links above indicate, there was a "sunspeck" reported August 21/22, though. Reader MikeyTheK adds a link to a story at Daily Tech on the spotless record.

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