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Comment Re:Its a trap! (Score 3, Insightful) 11

As far as I can tell nobody really has any consistent idea what "kill switch" is supposed to mean. Eg. https://ancillary-proxy.atarimworker.io?url=https%3A%2F%2Fwww.scientificamerican...

OpenAI and Anthropic already have kill switches, from the power cord through to account bans. If they don't want anyone using their model they can do that. Likewise, if the US government is sufficiently motivated to order a service provider to stop providing that service, they can absolutely do that. I get the feeling the actual companies are hoping they can implement something that has lots of buzzwords and does sort of what their "guard rails" do, and everyone will stop bugging them about it.

Naturally the FSF imagines some hypothetical technology that allows the government to reach into your home to shut off the matrix multiplies running on your own computer.

Comment Re:Damn... (Score 1) 25

the us has been fascist for a very long time

The US has been oligarchic and authoritarian all along, and has behaved towards some other nations much like a fascist nation would do, but in general has not subjected the general citizenry to full blown fascism. It's been horrible to everyone other than landed white males all along, though.

Comment Re:It's an ad programme for "new space" startups (Score 1) 88

Technology isn't really the problem. We've got most or all the technology to do what the GP suggested. What we lack are engineering experience, infrastructure and good economic reasons to do it.

Europe had all the technology required to build a casino in the Nevada desert in the 16th century, but it took four hundred years to get around to building the first one in Las Vegas.

Comment Re:We're probably going to find more (Score 2) 23

Deeply, deeply misleading comment.

First off, you're using a denominator fallacy. Yes, we have discovered over 200 types of HPV. Gardasil 9 targets 9 types, and numerically, yes, 9 / 200+ ~= 4-5%. But most of the 200 known types of HPV are rare and/or irrelevant (causing ordinary warts on fingers, knees, and feet, with extremely low odds of cancer). Only 40 types infect the mucosal/genital tract, and of those, only 12-14 are high risk. Gardasil 9 targets the 7 strains responsible for 90% of all cervical cancers, as well as types 6 and 11, that cause 90% of genital warts.

Secondly: cervical cancer indeed tends to happen in middle-aged women. But the disease itself is typically acquired in the teens or 20s. It's oncogenesis that takes decades to happen. Vaccination protects women of all ages.

I will however, admit that your claim that it "doesn't even target the HPV most likely to cause throat cancer in men" isn't misleading. Rather than being misleading, it's just simply false. HPV-associated oropharyngeal cancer is caused overwhelmingly by Type 16 (85-90% of all HPV-positive throat cancers). Even the original 4-variant Gardacil covered Type 16.

And, do I even need to add, that the claim that "Gardasil fatalities will have killed more teens than prevented deaths of women” is sheer unadulterated bullshit? There has been ZERO causal link found between Gardacil vaccination and death, by any major health organization (WHO, CDC, or EMA). This more stupid "I DiD mY oWn ReSeArCh" VAERS bullshit, where even a person dying in a car accident after getting vaccinated gets a report. VAERS isn't controlled. Stop pretending that it is. It flags signals for controlled research. It is not itself controlled research. Controlled research does not link Gardacil and death.

You know what the most common significant adverse reaction to Gardacil is? Vasocagal syncope. Sounds pretty terrifying, until you learn that that is "fainting from needle anxiety".

Check Falcaro et al, 2021, studying HPV vaccination in the UK - there's been an 87% reduction in cervical cancer rates and a 97% reduction in precancerous lesions. Australia is on track to effectively eliminate cervical cancer as a public health issue within a decade.
  vaccination coverage.

Also, do I even have to get into how stupid the notion of "get cancer, but then cure it" is? Cancer does damage. "Cures" do damage. Pain, infertility, disfigurement, etc. Your notion is "rely on some theoretical (deeply doubted by most researchers) notion of imminent magical perfect AI cancer cures" because of your ridiculous not-at-all-scientifically-backed antivax bullshit about a treatment that has been immensely effective and immensely safe.

Comment Re:If they are thermally efficient enough (Score 1) 88

There's lots of desert where nobody really cares what you do, and even more ocean. We don't like building in those places because they're far away from where we want to use the services, difficult and expensive to access, and have issues with cooling, power supply, etc.

But all those problems are worse in space, and you generally need to rebuild your entire infrastructure, from power plant to GPU, every five years or so.

Comment Re: We're probably going to find more (Score 1) 23

We have remnants of all sorts of viruses left around in our genome. My favourite example is parasitic wasps. They ended up evolving the ability to use viral genomes in their DNA as a weapon. Laying an egg inside another insect and having it mature in there is a big challenge, because their eggs' host's immune system starts attacking it. But it turned out to be advantageous for wasps to be infected, because they'd infect the host, hindering its immune system. The virus and wasp ended up coevolving, to the degree now that many parasitic wasps in effect produces virions on-demand, which do not harm the wasp, and instead serve only to suppress their eggs' host's immune system.

Comment Re:We're probably going to find more (Score 2) 23

And not just cancers. Look at the intro paragraphs to the Wikipedia article on Epstein-Barr, for example. It's like every year we discover a new link between it and some horrible disease. My mother has disabling neuropathy from Sjögrens; there's now some links between Sjögrens and EBV, and she has measured EBV reactivation.

In COVID, we discovered "Long COVID", and how disabling it was for victims. Not just Long COVID - e.g. obvious sequelae - but also a whole slew of other diseases (particularly cardiovascular and respiratory) have their probabilities shoot up dramatically in the six months post-infection, lesser increases after that. Yet as we started comparing it to other contageous diseases such as influenza, we started finding that even if SARS-CoV-2 is somewhat more at risk of causing debilitating sequelae (times how everyone was contracting it at once), influenza and other common viruses are also very capable of causing debilitating sequelae.

My father went from someone who was going on long hikes every day to prepare for hiking to Everest Base Camp to being unable to walk in a matter of days. He caught a virus on a plane, "got better", but then a couple weeks later, suddenly ended up in the hospital becoming rapidly paralyzed due to Guillain Barre. It nearly progressed to his lungs, but he was lucky to avoid intubation and to be an unusually-fast recovery case. Most aren't so lucky.

Just because you "got better" doesn't actually mean that you "got better". Pathogens deliberately disregulate your body in a vast range of ways (some in weird ways - for example, measles can cause your body to "forget" how to fight other infections that you were previously immune to!). Your innate immune system attacking them means deliberately doing damage to your body in the process. And the adaptive immune system runs the risk, with every infection, of accidentally learning to attack some part of your body instead. Even the very act of the immune system proliferating is itself a risk. Because of my mother's Sjögren's, the immune system was attacking her salivary glands. This led to extensive, nonstop lymphocyte propagation. Which in turn, led to MALT lymphoma. Your own immune system's activation can cause cancer.

It honestly shocked me that we went from all we learned during COVID to "pretending that nothing ever happened", just back to exactly how we were living before. No, we should absolutely not all be masking all the time. But can we at least clean our damned air, like we clean our water? Yes, if you're up close talking to someone, you should be able to get infected from them if they're sick; trying to prevent that is too difficult. But the person across the room should not be getting sick. You know what it reminds me so much of? The Broad Street cholera epidemic. It's well known that removing the handle from the Broad Street pump cured the infection, a victory for modern epidemiology and proving the hazards of contaminated water. But what's lesser known is the fact that as soon as the epidemic subsided, they put the handle right back on. People simply didn't want to think about the fact that their feces was leaking bacteria into their drinking water supply.

Also, to be clear: pathogens are not Pokémon: you do not need to catch them all. Yes, if there is no vaccine for a given common "mild" pathogen, it's usually good that children catch some variant of it once as a child, rather than first encountering it when they're 70 years old. But you do not need to catch every seasonal variant that goes around. Memory B and T cell immunity against severe outcomes is very durable. A virus shuffling up its receptor binding domain to evade immunity enough to cause a seasonal infection doesn't mean your body has to start over with learning how to not end up hospitalized from it.

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