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Average Ratings 0 Ratings
Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
Zochi stands out as the first autonomous AI system capable of completing the entire scientific research cycle, ranging from formulating hypotheses to achieving peer-reviewed publication, while generating cutting-edge outcomes. In contrast to previous systems that were confined to specific, well-defined tasks, Zochi thrives in confronting research challenges that are at the cutting edge of artificial intelligence. The system's effectiveness is demonstrated through a series of peer-reviewed papers accepted at the ICLR 2025 workshops, highlighting Zochi's capacity to produce innovative and academically sound contributions. Furthermore, Zochi recognized a significant obstacle within the AI field: the issue of cross-skill interference during parameter-efficient fine-tuning. This problem arises when models are adapted for multiple tasks at once, leading to enhancements in one skill that may negatively impact others. To combat this challenge, Zochi introduced a novel approach called CS-ReFT (Compositional Subspace Representation Fine-tuning), which emphasizes the editing of representations instead of altering weights. This groundbreaking method has the potential to revolutionize how AI systems are fine-tuned for diverse applications.
API Access
Has API
Yes
API Access
Has API
No
Integrations
Biohub
No
Python
No
Pricing Details
Free
Free Trial
No
Free Version
Yes
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
Intology
Founded
2025
Country
United States
Website
www.intology.ai/blog/zochi-tech-report
Product Features
Product Features
Artificial Intelligence
Chatbot
No
For Healthcare
No
For Sales
No
For eCommerce
No
Image Recognition
No
Machine Learning
No
Multi-Language
No
Natural Language Processing
No
Predictive Analytics
No
Process/Workflow Automation
No
Rules-Based Automation
No
Virtual Personal Assistant (VPA)
No