Average Ratings 0 Ratings
Average Ratings 0 Ratings
Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
Microsoft has introduced Muse, an innovative generative AI model poised to transform the way gameplay concepts are developed. In partnership with Ninja Theory, this World and Human Action Model (WHAM) draws training data from the game Bleeding Edge, granting it a profound grasp of 3D game landscapes, including the intricacies of physics and player interactions. This capability allows Muse to generate varied and coherent gameplay sequences, which can enhance the creative process for developers. Additionally, the AI is capable of creating game visuals and anticipating controller actions, streamlining prototyping and artistic exploration in game design. By leveraging an analysis of over 1 billion images and actions, Muse showcases its potential not only for game creation but also for game preservation, as it can recreate classic titles for contemporary gaming platforms. Despite being in its initial phases, with output currently limited to a resolution of 300×180 pixels, Muse signifies a pivotal step forward in harnessing AI to support game development, with the goal of amplifying human creativity rather than supplanting it. As Muse evolves, it may open up new avenues for both game innovation and the revival of beloved gaming classics.
API Access
Has API
Yes
API Access
Has API
No
Integrations
Biohub
Yes
Claude Fable 5.1
No
Claude Mythos 5
No
Claude Opus 5
No
Claude Opus 5.5
No
GPT-5.4 mini
No
GPT-5.4 nano
No
GPT-5.6 Sol Ultrafast
No
GPT-5.6 Terra
No
GPT-6 Astra
No
Integrations
Biohub
No
Claude Fable 5.1
Yes
Claude Mythos 5
Yes
Claude Opus 5
Yes
Claude Opus 5.5
Yes
GPT-5.4 mini
Yes
GPT-5.4 nano
Yes
GPT-5.6 Sol Ultrafast
Yes
GPT-5.6 Terra
Yes
GPT-6 Astra
Yes
Pricing Details
Free
Free Trial
No
Free Version
Yes
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
Yes
Live Rep (24/7)
No
Online Support
Yes
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Types of Training
Training Docs
Yes
Webinars
Yes
Live Training (Online)
Yes
In Person
Yes
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
Microsoft
Founded
1975
Country
United States
Website
microsoft.com