Best Healthcare Integration Engines for Linux of 2025

InterSystems IRIS, a cloud-first data platform, is a multi-model transactional database management engine, application development platform, interoperability engine and open analytics platform. InterSystems IRIS offers a variety of APIs that allow you to work with transactional persistent data simultaneously. These include key-value, relational and object, document, and multidimensional. Data can be managed by SQL, Java, node.js, .NET, C++, Python, and native server-side ObjectScript language. InterSystems IRIS features an Interoperability engine as well as modules for building AI solutions. InterSystems IRIS features horizontal scalability (sharding and ECP), and High Availability features such as Business intelligence, transaction support and backup.

The Iguana® integration engine delivers a rapid, reliable, and scalable interoperability solution for healthcare organizations through the acquisition and exchange of healthcare information. Connect all message formats: HL7, FHIR, X12, JSON and more.

The Qvera Interface Engine (QIE) serves as a robust integration platform within the healthcare sector, aimed at enhancing interoperability among diverse healthcare systems. It accommodates an extensive array of standards, such as HL7, FHIR, DICOM, CDA, JSON, CSV, XML, and X12, which promotes effective data sharing among electronic health records, imaging systems, and health information exchanges. QIE provides versatile deployment options, permitting installations either on-premises or within cloud environments like AWS, Azure, Google Cloud Platform, and IBM Cloud. With its user-friendly drag-and-drop visual channel editor, the platform streamlines the process of developing and managing interfaces, making it accessible for users. The engine guarantees high availability with an impressive uptime of 99.999% and adheres to SOC 2 Type 2 compliance, reflecting its dedication to both security and reliability. Additionally, QIE's capabilities empower healthcare organizations to adapt swiftly to evolving technological demands and regulatory standards.