Best Free Healthcare Integration Engines of 2025

InterSystems IRIS, a cloud-first data platform, is a multi-model transactional database management engine, application development platform, interoperability engine and open analytics platform. InterSystems IRIS offers a variety of APIs that allow you to work with transactional persistent data simultaneously. These include key-value, relational and object, document, and multidimensional. Data can be managed by SQL, Java, node.js, .NET, C++, Python, and native server-side ObjectScript language. InterSystems IRIS features an Interoperability engine as well as modules for building AI solutions. InterSystems IRIS features horizontal scalability (sharding and ECP), and High Availability features such as Business intelligence, transaction support and backup.

eMedicalPractice is a healthcare technology company based in Delray Beach, Florida. Since 2008, we have offered ambulatory practices and medical management groups an arsenal of fully integrated and highly customizable enterprise solutions including our Electronic Health Record (EHR), Practice Management, Telemedicine, Clearinghouse, Revenue Cycle Management, Billing, Patient Engagement and MIPS Registry platforms.

We assist you in achieving your objectives by minimizing expenses, enhancing clinical results, lowering readmission rates, and boosting revenue streams. Amplify your income through mobile charge capture, efficient clinical documentation, medical billing, and optimizing revenue collection with our state-of-the-art technology tailored specifically for healthcare professionals. With MediMobile®, you can conveniently arrange your rounds and appointments in advance or spontaneously, utilizing your handheld device or any internet-enabled browser. You have the flexibility to organize your rounds and appointments based on various criteria such as location, date, room number, or provider name, and you can also collaborate seamlessly with colleagues in your practice. The platform is fully customizable to adapt to your unique preferences. MediMobile® provides an extensive array of reporting features suitable for both beginner users and seasoned data analysts. Furthermore, MediMobile®’s intelligent technology integration engine facilitates real-time connections with hospital systems, patient management software, and billing solutions, ensuring a streamlined workflow that enhances efficiency and effectiveness in healthcare delivery.

Dynamic Health serves as a comprehensive, evidence-driven resource aimed at empowering nurses and allied health practitioners to enhance their skills, quickly find answers to clinical queries, and cultivate a commitment to evidence-based practices and critical analysis that ultimately leads to better patient care. The EBSCO team has expanded the already extensive content of Dynamic Health, now incorporating detailed discussions on evidence-based topics related to diseases and conditions, including their signs, symptoms, diagnostic tests, and care interventions, all tailored to meet the decision-making requirements of healthcare professionals. Furthermore, Dynamic Health simplifies the process of obtaining continuing education units (CEUs) through its integrated learning system, allowing users to earn credits while addressing clinical inquiries. This resource also provides a comprehensive overview of various diseases and conditions, along with valuable insights on abnormalities that may signify underlying medical issues, thereby enhancing the interprofessional team's ability to deliver quality care. By bridging the gap between knowledge and practice, Dynamic Health equips healthcare providers with the necessary tools to support informed decision-making and improve overall patient outcomes.

Mirth Connect, developed by NextGen Healthcare, stands out as a premier open-source integration engine in the healthcare sector, aimed at enhancing interoperability among various healthcare systems. It accommodates a range of messaging standards like HL7, FHIR, and DICOM, facilitating smooth data transfers between differing applications. The platform is designed with a user-friendly interface that incorporates both drag-and-drop features and advanced scripting options, empowering users to create, test, and implement customized interfaces that meet their unique requirements. With its platform-agnostic nature, Mirth Connect guarantees compatibility across multiple systems and technologies, while also being equipped to manage high-volume and high-throughput operations, making it ideal for healthcare organizations of varying sizes. Additionally, for users looking for more robust features and specialized support, Mirth Connect Premium offers advanced functionalities such as SSL and certificate management, FHIR connectors, and access to extensive training and certification programs, ensuring users can maximize their integration capabilities. This comprehensive approach helps organizations improve their operational efficiency and enhances the overall quality of patient care.

CareBridge, developed by Med Tech Solutions, is a certified platform for EHR integration that is neutral to vendors. It enhances the ease of data exchange, management, and accessibility among diverse healthcare organizations and information systems by connecting Electronic Health Records (EHR) with other health technology infrastructures. Acting as a central hub, CareBridge ensures that messages can transition smoothly between various sources and destinations. Its comprehensive, web-based management console provides organizations the ability to monitor the status of interfaces, thereby reducing the likelihood of integration downtime. Supporting multiple data formats and standards like HL7, JSON, XML, flat files, and EDI/X12, the platform guarantees compatibility across a broad spectrum of systems. CareBridge offers adaptable deployment alternatives, including on-premises setups, cloud hosting, or an Integration Platform as a Service (iPaaS), making it capable of evolving alongside your organization’s needs. Furthermore, its robust capabilities position it as an essential tool for improving interoperability within the healthcare sector.