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Average Ratings 0 Ratings

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ease
features
design
support

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Write a Review

Description

Loupe Browser stands out as a robust visualization tool, offering the user-friendly capabilities essential for delving into and interpreting 10x Genomics Chromium and Visium datasets. Additionally, the LoupeR package facilitates the transformation of Seurat objects into files compatible with Loupe Browser. The interactive features of the Loupe Browser interface are exemplified through its use of a lung squamous cell carcinoma dataset. Central to the user experience is the view panel, where individual points, each representing cell barcodes, are displayed across multiple projections. Each point typically corresponds to a single cell’s barcode, enabling focused analysis. The t-SNE plot generated by the cell ranger pipeline serves as the default projection, while alternative visualization options are also accessible. Users can effortlessly reposition the plot by dragging the mouse over the cells and can zoom in or out using the mouse wheel or trackpad. Moreover, as the mouse hovers over the plot, cluster labels become visible, which proves particularly beneficial when working with datasets that contain numerous precomputed clusters. This capability enhances the analytical experience, making it easier to identify and interpret complex data patterns.

Description

VSClinical facilitates the clinical analysis of genetic variants in accordance with ACMG and AMP guidelines. Its structured workflow supports adherence to the American College of Medical Genetics (ACMG) standards, which are essential for identifying and categorizing pathogenic variants related to inherited disease risk, cancer susceptibility, and rare disease diagnosis. The combined ACMG/AMP guidelines for variant interpretation establish a framework for scoring variants and categorizing them into one of five classification levels. Implementing these guidelines necessitates a thorough examination of annotations, genomic contexts, and pre-existing clinical insights for each variant. VSClinical streamlines this process by offering a customized workflow that evaluates each relevant criterion and supplies comprehensive bioinformatics, literature references, and clinical knowledgebase evidence to aid in the scoring and interpretation of variants. This innovative approach is designed to enhance the efficiency of variant scientists as they navigate the complexities of variant processing and analysis. Overall, VSClinical stands out as a vital tool for accelerating the understanding and classification of genetic variants in clinical settings.

API Access

Has API No 

API Access

Has API No 

Screenshots View All

Screenshots View All

Integrations

GenomeBrowse No 
VarSeq No 

Integrations

GenomeBrowse Yes 
VarSeq Yes 

Pricing Details

No price information available.
Free Trial No 
Free Version No 

Pricing Details

No price information available.
Free Trial Yes 
Free Version No 

Deployment

Web-Based No 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows Yes 
Mac Yes 
Linux Yes 
Chromebook No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Customer Support

Business Hours Yes 
Live Rep (24/7) No 
Online Support Yes 

Customer Support

Business Hours Yes 
Live Rep (24/7) No 
Online Support Yes 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person Yes 

Types of Training

Training Docs Yes 
Webinars Yes 
Live Training (Online) Yes 
In Person Yes 

Vendor Details

Company Name

10x Genomics

Founded

2012

Country

United States

Website

www.10xgenomics.com/support/software/loupe-browser/latest

Vendor Details

Company Name

Golden Helix

Founded

1998

Country

United States

Website

www.goldenhelix.com/products/VarSeq/vsclinical.html

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