Average Ratings 0 Ratings
Average Ratings 0 Ratings
Description
Evo 2 represents a cutting-edge genomic foundation model that excels in making predictions and designing tasks related to DNA, RNA, and proteins. It employs an advanced deep learning architecture that allows for the modeling of biological sequences with single-nucleotide accuracy, achieving impressive scaling of both compute and memory resources as the context length increases. With a robust training of 40 billion parameters and a context length of 1 megabase, Evo 2 has analyzed over 9 trillion nucleotides sourced from a variety of eukaryotic and prokaryotic genomes. This extensive dataset facilitates Evo 2's ability to conduct zero-shot function predictions across various biological types, including DNA, RNA, and proteins, while also being capable of generating innovative sequences that maintain a plausible genomic structure. The model's versatility has been showcased through its effectiveness in designing operational CRISPR systems and in the identification of mutations that could lead to diseases in human genes. Furthermore, Evo 2 is available to the public on Arc's GitHub repository, and it is also incorporated into the NVIDIA BioNeMo framework, enhancing its accessibility for researchers and developers alike. Its integration into existing platforms signifies a major step forward for genomic modeling and analysis.
Description
Swiss-PdbViewer, also known as DeepView, is a software tool that offers an intuitive interface for the simultaneous analysis of multiple proteins. Users can superimpose these proteins to determine structural alignments and evaluate various critical components, such as active sites. The application simplifies the process of obtaining information on amino acid mutations, hydrogen bonds, angles, and atomic distances through its easy-to-navigate graphical and menu-driven interface. Developed by Nicolas Guex since 1994, Swiss-PdbViewer was originally closely integrated with SWISS-MODEL, an automated homology modeling server created by the Swiss Institute of Bioinformatics (SIB) within the Structural Bioinformatics Group at the Biozentrum in Basel. Over time, the SWISS-MODEL web interface has progressed significantly, allowing for direct use in advanced modeling tasks. As a result, the complexity of maintaining a direct connection with Swiss-PdbViewer has led to the discontinuation of support for that integration. This evolution reflects broader changes in bioinformatics tools and their capabilities.
API Access
Has API
No
API Access
Has API
No
Integrations
Evo Designer
Yes
GitHub
Yes
Hugging Face
Yes
NVIDIA BioNeMo
Yes
Integrations
Evo Designer
No
GitHub
No
Hugging Face
No
NVIDIA BioNeMo
No
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
No
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
Yes
Mac
Yes
Linux
Yes
Chromebook
No
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
Yes
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Vendor Details
Company Name
Arc Institute
Country
United States
Website
arcinstitute.org/tools/evo
Vendor Details
Company Name
Swiss-PdbViewer
Founded
1994
Country
Switzerland
Website
spdbv.unil.ch/