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Description
Brainlab's Elements Contrast Clearance Analysis is an MRI-based technique aimed at distinguishing areas of contrast clearance and accumulation within brain tumor imaging datasets. This advanced high-resolution analysis enhances the understanding required for ongoing evaluations and decision-making across various clinical fields, including radiosurgery, radiation oncology, neurosurgery, neuro-oncology, and neuroradiology. The methodology entails capturing two standard 3D T1-weighted MRIs; the first scan is taken around 5 minutes after administering a standard dose of contrast agent, while the second scan occurs 60 to 105 minutes later. By subtracting the initial series from the subsequent one, volumetric maps are created that clearly identify zones of contrast clearance (shown in blue) against those of contrast accumulation (illustrated in red). These findings empower clinicians to better evaluate the effects of radiation treatment in contrast to potential tumor regrowth, allowing for more educated decisions regarding both initial and subsequent treatment plans. As a result, this analysis not only aids in clinical assessments but also enhances the overall management of patient care in complex cases.
Description
The foundational aspect of our immunotherapy approach lies in our comprehension of antigens and neoantigens, particularly in identifying which variations will be transcribed, translated, processed, and subsequently displayed on the surface of cells via Human leukocyte antigen (HLA) molecules, thus making them recognizable to T cells. We achieve this by employing Gritstone EDGETM, a unique platform powered by machine learning. Creating cancer immunotherapies that incorporate tumor-specific neoantigens proves challenging, mainly because tumors consist of numerous mutations, yet only a fraction of these lead to genuine tumor-specific neoantigens. To tackle this complexity, we have developed EDGE's cutting-edge integrated neural network model, trained with millions of data points gathered from a diverse range of tumor and normal tissue samples across various patient ancestries. This extensive training allows us to enhance the accuracy of neoantigen identification and improve the effectiveness of our immunotherapy strategies.
API Access
Has API
API Access
Has API
Integrations
No details available.
Integrations
No details available.
Pricing Details
No price information available.
Free Trial
Free Version
Pricing Details
No price information available.
Free Trial
Free Version
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Vendor Details
Company Name
Brainlab
Founded
1989
Country
Germany
Website
www.brainlab.com/radiosurgery-products/elements/contrast-clearance-analysis/
Vendor Details
Company Name
Gritstone bio
Founded
2015
Country
United States
Website
gritstonebio.com/scientific-platform/
Product Features
Medical Imaging
Automated Routing
Comparison View
Compliance Management
Data Import / Export
Diagnostic Reporting
Image Analytics
Treatment Planning
Workflow Management
