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Description

ESMFold demonstrates how artificial intelligence can equip us with innovative instruments to explore the natural world, akin to the way the microscope revolutionized our perception by allowing us to observe the minute details of life. Through AI, we can gain a fresh perspective on the vast array of biological diversity, enhancing our comprehension of life sciences. A significant portion of AI research has been dedicated to enabling machines to interpret the world in a manner reminiscent of human understanding. However, the complex language of proteins remains largely inaccessible to humans and has proven challenging for even the most advanced computational systems. Nevertheless, AI holds the promise of unlocking this intricate language, facilitating our grasp of biological processes. Exploring AI within the realm of biology not only enriches our understanding of life sciences but also sheds light on the broader implications of artificial intelligence itself. Our research highlights the interconnectedness of various fields: the large language models powering advancements in machine translation, natural language processing, speech recognition, and image synthesis also possess the capability to assimilate profound insights about biological systems. This cross-disciplinary approach could pave the way for unprecedented discoveries in both AI and biology.

Description

Evo 2 represents a cutting-edge genomic foundation model that excels in making predictions and designing tasks related to DNA, RNA, and proteins. It employs an advanced deep learning architecture that allows for the modeling of biological sequences with single-nucleotide accuracy, achieving impressive scaling of both compute and memory resources as the context length increases. With a robust training of 40 billion parameters and a context length of 1 megabase, Evo 2 has analyzed over 9 trillion nucleotides sourced from a variety of eukaryotic and prokaryotic genomes. This extensive dataset facilitates Evo 2's ability to conduct zero-shot function predictions across various biological types, including DNA, RNA, and proteins, while also being capable of generating innovative sequences that maintain a plausible genomic structure. The model's versatility has been showcased through its effectiveness in designing operational CRISPR systems and in the identification of mutations that could lead to diseases in human genes. Furthermore, Evo 2 is available to the public on Arc's GitHub repository, and it is also incorporated into the NVIDIA BioNeMo framework, enhancing its accessibility for researchers and developers alike. Its integration into existing platforms signifies a major step forward for genomic modeling and analysis.

API Access

Has API No 

API Access

Has API No 

Screenshots View All

Screenshots View All

Integrations

Evo Designer No 
GitHub No 
Hugging Face No 
NVIDIA BioNeMo No 

Integrations

Evo Designer Yes 
GitHub Yes 
Hugging Face Yes 
NVIDIA BioNeMo Yes 

Pricing Details

Free
Free Trial No 
Free Version Yes 

Pricing Details

No price information available.
Free Trial No 
Free Version No 

Deployment

Web-Based Yes 
On-Premises Yes 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support Yes 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person Yes 

Vendor Details

Company Name

Meta

Founded

2004

Country

United States

Website

github.com/facebookresearch/esm

Vendor Details

Company Name

Arc Institute

Country

United States

Website

arcinstitute.org/tools/evo

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Alternatives

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