Average Ratings 0 Ratings
Average Ratings 1 Rating
Description
Aurora utilizes principles of quantum mechanics and thermodynamics alongside a sophisticated continuous water model to assess the solvation effects on ligand binding affinities. This methodology is significantly different from the traditional scoring functions typically employed for predicting binding affinities. By integrating entropy and aqueous electrostatic contributions directly into the computations, Aurora's algorithms yield far more precise and reliable binding free energy values. The interaction between a ligand and a protein is fundamentally defined by the binding free energy value. This free energy (F) serves as a thermodynamic measure that correlates directly with the experimentally determined inhibition constant (IC50), influenced by factors such as electrostatic interactions, quantum effects, aqueous solvation forces, and the statistical characteristics of the molecules involved. Non-additivity in F arises primarily from two key components: the electrostatic and solvation energy, and the entropy, which together contribute to the complexity of ligand-protein interactions. Understanding these contributions is essential for the accurate prediction of binding affinities in drug design and molecular biology.
Description
Entropy offers a seamless, secure transition from your trusted circle to your digital assets in the event of an emergency.
Security that is User-Friendly
Entropy allows you to securely partition your important information into discrete share, which each do not reveal anything about your secret without the other. Distribute them to a small group of trusted people who can store them offline.
Long-Term Resilience
Entropy's robust security features include 256-bit encryption. This allows for decentralized, durable offline storage that protects your data against both online and offline threats.
API Access
Has API
No
API Access
Has API
No
Integrations
Amazon
No
Android
No
Apple iOS
No
Arch Linux
No
Backblaze
No
BitLocker
No
Bitcoin
No
Ethereum
No
MetaMask
No
Windows 11
No
Integrations
Amazon
Yes
Android
Yes
Apple iOS
Yes
Arch Linux
Yes
Backblaze
Yes
BitLocker
Yes
Bitcoin
Yes
Ethereum
Yes
MetaMask
Yes
Windows 11
Yes
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Pricing Details
$24.99
Free Trial
No
Free Version
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
No
On-Premises
No
iPhone App
Yes
iPad App
Yes
Android App
Yes
Windows
No
Mac
No
Linux
No
Chromebook
No
Customer Support
Business Hours
Yes
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Types of Training
Training Docs
No
Webinars
No
Live Training (Online)
No
In Person
No
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Vendor Details
Company Name
Aurora Fine Chemicals
Founded
1990
Country
United States
Website
aurorafinechemicals.com/drug-discovery-software.html
Vendor Details
Company Name
Quantum Entropy
Founded
2023
Country
Australia
Website
entropykey.com