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Average Ratings 0 Ratings

Total
ease
features
design
support

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Write a Review

Description

Aurora manages applications and services across a communal array of machines, ensuring their continuous operation. In the event of machine failures, Aurora adeptly reallocates those jobs to functioning machines. During job updates, it assesses the health and status of the deployment, automatically reverting changes if required. To ensure that certain applications receive guaranteed resources, Aurora employs a quota system and accommodates multiple users for service deployment. The services are highly customizable through a Domain-Specific Language (DSL) that facilitates templating, which helps in creating standard patterns and reducing repetitive configurations. Additionally, Aurora communicates the services to Apache ZooKeeper, enabling client discovery through tools like Finagle. This comprehensive approach allows for efficient management and deployment of services in a dynamic environment.

Description

Aurora utilizes principles of quantum mechanics and thermodynamics alongside a sophisticated continuous water model to assess the solvation effects on ligand binding affinities. This methodology is significantly different from the traditional scoring functions typically employed for predicting binding affinities. By integrating entropy and aqueous electrostatic contributions directly into the computations, Aurora's algorithms yield far more precise and reliable binding free energy values. The interaction between a ligand and a protein is fundamentally defined by the binding free energy value. This free energy (F) serves as a thermodynamic measure that correlates directly with the experimentally determined inhibition constant (IC50), influenced by factors such as electrostatic interactions, quantum effects, aqueous solvation forces, and the statistical characteristics of the molecules involved. Non-additivity in F arises primarily from two key components: the electrostatic and solvation energy, and the entropy, which together contribute to the complexity of ligand-protein interactions. Understanding these contributions is essential for the accurate prediction of binding affinities in drug design and molecular biology.

API Access

Has API Yes 

API Access

Has API No 

Screenshots View All

Screenshots View All

Integrations

Apache Mesos Yes 
Beats Yes 
Cloud Ops Group Yes 
Kapacitor Yes 
Paessler PRTG Hosted Monitor Yes 
cBackup Yes 

Integrations

Apache Mesos No 
Beats No 
Cloud Ops Group No 
Kapacitor No 
Paessler PRTG Hosted Monitor No 
cBackup No 

Pricing Details

No price information available.
Free Trial No 
Free Version No 

Pricing Details

No price information available.
Free Trial No 
Free Version No 

Deployment

Web-Based No 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows Yes 
Mac Yes 
Linux Yes 
Chromebook No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support No 

Customer Support

Business Hours Yes 
Live Rep (24/7) No 
Online Support Yes 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Types of Training

Training Docs No 
Webinars No 
Live Training (Online) No 
In Person No 

Vendor Details

Company Name

Apache Software Foundation

Founded

1999

Country

United States

Website

aurora.apache.org

Vendor Details

Company Name

Aurora Fine Chemicals

Founded

1990

Country

United States

Website

aurorafinechemicals.com/drug-discovery-software.html

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Product Features

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